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Hakon Leffler Selected Research

Galactosides

1/2018Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain.
4/2012Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

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Hakon Leffler Research Topics

Disease

32Neoplasms (Cancer)
01/2022 - 01/2002
13Inflammation (Inflammations)
01/2018 - 01/2002
8Neoplasm Metastasis (Metastasis)
01/2022 - 06/2003
6Fibrosis (Cirrhosis)
06/2019 - 03/2012
6Breast Neoplasms (Breast Cancer)
06/2018 - 06/2003
3Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2016 - 03/2012
2Ulcerative Colitis
01/2016 - 08/2002
2Hepatitis
02/2015 - 06/2012
2Glomerulonephritis
09/2012 - 04/2012
2Nephritis
09/2012 - 04/2012
2Infections
04/2010 - 10/2002
1Arthritis (Polyarthritis)
01/2022
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022
1Respiratory Tract Diseases (Respiratory Tract Disease)
01/2022
1Idiopathic Pulmonary Fibrosis
01/2021
1Stomach Neoplasms (Stomach Cancer)
01/2021
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019
1Alzheimer Disease (Alzheimer's Disease)
01/2019
1Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
01/2019
1Adenocarcinoma of Lung
01/2019
1Corneal Neovascularization
01/2017
1Burns
01/2017
1Chronic Renal Insufficiency
01/2017
1Disease Progression
02/2016
1Stroke (Strokes)
03/2015
1Synucleinopathies
11/2014
1Asthma (Bronchial Asthma)
09/2012
1Renal Insufficiency (Renal Failure)
04/2012
1Interstitial Lung Diseases (Interstitial Lung Disease)
03/2012
1Melanoma (Melanoma, Malignant)
12/2010
1Papillary Thyroid Cancer
10/2009
1Hyperplasia
04/2009
1Prostatic Neoplasms (Prostate Cancer)
12/2008
1Peripheral Nerve Injuries
05/2007

Drug/Important Bio-Agent (IBA)

25Galectin 3 (LGALS3)IBA
01/2022 - 10/2002
17Galectins (Galectin)IBA
01/2022 - 01/2002
13Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2004
10Galectin 1 (LGALS1)IBA
01/2018 - 07/2006
9LectinsIBA
01/2022 - 05/2007
7CarbohydratesIBA
01/2022 - 01/2004
6Carrier Proteins (Binding Protein)IBA
12/2019 - 05/2005
5LigandsIBA
08/2019 - 07/2006
4Polysaccharides (Glycans)IBA
01/2022 - 01/2016
4Galactose (Galactopyranose)FDA LinkGeneric
12/2019 - 03/2012
4Galectin 4 (LGALS4)IBA
02/2016 - 01/2004
3saccharide-binding proteinsIBA
11/2021 - 11/2014
3Bleomycin (Blenoxane)FDA LinkGeneric
01/2016 - 03/2012
3Immunoglobulin A (IgA)IBA
09/2012 - 08/2002
3Glycoproteins (Glycoprotein)IBA
09/2012 - 01/2011
3DisaccharidesIBA
12/2010 - 07/2005
2Pharmaceutical PreparationsIBA
01/2022 - 01/2016
2CateninsIBA
01/2021 - 03/2012
2GalactosidesIBA
01/2018 - 04/2012
2coumarinIBA
01/2018 - 01/2016
2AntibodiesIBA
01/2016 - 08/2002
2Biomarkers (Surrogate Marker)IBA
09/2012 - 01/2011
2beta-galactosideIBA
04/2010 - 05/2005
2LactoseFDA LinkGeneric
07/2006 - 07/2005
1MucinsIBA
01/2022
1Therapeutic UsesIBA
01/2021
1Immune Checkpoint InhibitorsIBA
01/2019
1Amyloid beta-PeptidesIBA
01/2019
1citrus pectinIBA
01/2019
1Peptides (Polypeptides)IBA
01/2019
1IonsIBA
06/2018
1salinomycinIBA
06/2018
1indolizineIBA
01/2018
1quinolineIBA
01/2018
1Silver NitrateIBA
01/2017
1Connective Tissue Growth FactorIBA
01/2017
1PectinsIBA
06/2016
1pirfenidoneIBA
01/2016
1Galectin 2 (LGALS2)IBA
01/2016
1LipopolysaccharidesIBA
03/2015
1Galactosylceramides (Galactocerebrosides)IBA
02/2015
1GlycolipidsIBA
02/2015
1SynucleinsIBA
11/2014
1galactose-binding proteinIBA
07/2013
1Tumor Biomarkers (Tumor Markers)IBA
09/2012
1Blood Proteins (Serum Proteins)IBA
09/2012
1EnzymesIBA
06/2012
1Concanavalin AIBA
06/2012
1CytokinesIBA
06/2012
1Antigen-Antibody Complex (Immune Complex)IBA
04/2012
1Transforming Growth Factors (Transforming Growth Factor)IBA
03/2012
1CollagenIBA
03/2012
1Angiogenic ProteinsIBA
04/2011
1HaptoglobinsIBA
01/2011
1Immunoglobulin M (IgM)IBA
01/2011
1GlycoconjugatesIBA
11/2010
1SugarsIBA
11/2010
1GlycosidesIBA
11/2010
1Immunoglobulin D (IgD)IBA
04/2009
1EstersIBA
12/2008
1thiodigalactosideIBA
12/2008

Therapy/Procedure

6Therapeutics
01/2022 - 06/2003
2Oral Administration
01/2019 - 01/2016
1Cautery
01/2017
1Drug Therapy (Chemotherapy)
10/2009